Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268783 | 0.89 | FBP1 (0.39) | PIK3CDDGAT1ADORA2AADORA1CNR1 | |
| SCHEMBL31269050 | 0.85 | PIK3CD (0.34) | PIK3CDDGAT1CNR1 | |
| SCHEMBL31269102 | 0.85 | PIK3CD (0.35) | PIK3CDDGAT1ROCK2CNR1CNR2 | |
| SCHEMBL31268747 | 0.85 | CNR1 (0.36) | PIK3CDDGAT1CNR1CNR2MEN1 | |
| SCHEMBL31269438 | 0.85 | PIK3CD (0.34) | PIK3CDDGAT1CNR1CNR2 | |
| SCHEMBL31269290 | 0.85 | PIK3CD (0.37) | PIK3CDDGAT1ROCK2ADORA2AADORA1 | |
| SCHEMBL31269283 | 0.85 | PIK3CD (0.38) | PIK3CDDGAT1CNR1CNR2ALDH1A1 | |
| SCHEMBL31269348 | 0.84 | PIK3CD (0.34) | PIK3CDDGAT1 | |
| SCHEMBL31269084 | 0.84 | PIK3CD (0.34) | PIK3CDDGAT1CNR1CNR2ALDH1A1 | |
| SCHEMBL31268788 | 0.83 | PIK3CD (0.37) | PIK3CDDGAT1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |