Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268783 | 0.87 | FBP1 (0.39) | PIK3CDDGAT1 | |
| SCHEMBL31269084 | 0.85 | PIK3CD (0.34) | PIK3CDDGAT1 | |
| SCHEMBL31269283 | 0.85 | PIK3CD (0.38) | PIK3CDDGAT1SMN1; SMN2 | |
| SCHEMBL31269050 | 0.84 | PIK3CD (0.34) | PIK3CDDGAT1 | |
| SCHEMBL31269001 | 0.84 | PIK3CD (0.34) | PIK3CDDGAT1 | |
| SCHEMBL31269277 | 0.84 | PIK3CD (0.35) | PIK3CDDGAT1 | |
| SCHEMBL31269438 | 0.83 | PIK3CD (0.34) | PIK3CDDGAT1 | |
| SCHEMBL31269290 | 0.83 | PIK3CD (0.37) | PIK3CDDGAT1 | |
| SCHEMBL31268799 | 0.83 | DGAT1 (0.35) | PIK3CDDGAT1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31268788 | 0.83 | PIK3CD (0.37) | PIK3CDDGAT1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |