SCHEMBL31268783

SCHEMBL31268783

CC1(Oc2ncnc3c2nc(-c2ccc(CC(N)=O)cc2Cl)n3CCc2ccccc2)CC1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 8/20 0.39
▸ PIK3CD O00329 2/20 0.36
▸ CNR1 P21554 5/20 0.36
▸ CNR2 P34972 5/20 0.36
▸ DGAT1 O75907 1/20 0.35
▸ ADORA2A P29274 1/20 0.35
▸ ADORA1 P30542 1/20 0.35
▸ CASR P41180 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31269290 0.93 PIK3CD (0.37) PIK3CDCNR1CNR2DGAT1ADORA2A
SCHEMBL31269001 0.89 PIK3CD (0.34) PIK3CDCNR1CNR2DGAT1ADORA2A
SCHEMBL31269438 0.88 PIK3CD (0.34) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269283 0.88 PIK3CD (0.38) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269084 0.87 PIK3CD (0.34) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269348 0.87 PIK3CD (0.34) PIK3CDDGAT1
SCHEMBL31269050 0.87 PIK3CD (0.34) PIK3CDCNR1DGAT1
SCHEMBL31268878 0.87 PIK3CD (0.36) PIK3CDCNR1CNR2DGAT1
SCHEMBL31269133 0.87 PLA2G2A (0.38) PIK3CDCNR1CNR2DGAT1
SCHEMBL31268747 0.87 CNR1 (0.36) PIK3CDCNR1CNR2DGAT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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