SCHEMBL31269438

SCHEMBL31269438

CC1(Oc2ncnc3c2nc(-c2ccc(CC(N)=O)cc2Cl)n3CCc2cccc(Br)n2)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.34
▸ DGAT1 O75907 1/20 0.33
▸ SRC P12931 1/20 0.32
▸ WEE1 P30291 1/20 0.32
▸ CNR1 P21554 1/20 0.31
▸ CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268783 0.88 FBP1 (0.39) PIK3CDDGAT1CNR1CNR2
SCHEMBL31269129 0.85 PIK3CD (0.35) PIK3CDDGAT1SRCWEE1CNR1
SCHEMBL31269001 0.85 PIK3CD (0.34) PIK3CDDGAT1CNR1CNR2
SCHEMBL31269290 0.84 PIK3CD (0.37) PIK3CDDGAT1CNR1CNR2
SCHEMBL31269283 0.84 PIK3CD (0.38) PIK3CDDGAT1CNR1CNR2
SCHEMBL31269084 0.83 PIK3CD (0.34) PIK3CDDGAT1CNR1CNR2
SCHEMBL31269348 0.83 PIK3CD (0.34) PIK3CDDGAT1
SCHEMBL31269050 0.83 PIK3CD (0.34) PIK3CDDGAT1CNR1
SCHEMBL31269133 0.83 PLA2G2A (0.38) PIK3CDDGAT1CNR1CNR2
SCHEMBL30983368 0.83 PIK3CD (0.36) PIK3CDDGAT1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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