Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IL18 | Q14116 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270776 | 0.93 | NISCH (0.55) | NISCHPPARGACHERUVBL1UBE2N | |
| SCHEMBL31270626 | 0.85 | MAPT (0.54) | LMNAKMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL31270741 | 0.85 | NISCH (0.52) | NISCHPPARGACHERUVBL1UBE2N | |
| SCHEMBL31270936 | 0.80 | PPARG (0.47) | NISCHPPARGACHEUBE2NLMNA | |
| SCHEMBL31270763 | 0.77 | NISCH (0.60) | NISCHPPARGACHERUVBL1UBE2N | |
| SCHEMBL31245424 | 0.75 | ACHE (0.56) | NISCHPPARGACHEUBE2NLMNA | |
| SCHEMBL29175165 | 0.75 | ACHE (0.81) | NISCHPPARGACHEUBE2NLMNA | |
| SCHEMBL13132676 | 0.74 | GABRA1 (0.42) | LMNAKMT2APOLBKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1142840 | 0.74 | ACHE (0.79) | NISCHPPARGACHEUBE2NLMNA | |
| SCHEMBL31270689 | 0.73 | PPARG (0.56) | NISCHPPARGACHERUVBL1UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |