Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31273874 | 0.85 | EIF4A3 (0.56) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL8828102 | 0.83 | KDM4E (0.53) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL31273240 | 0.82 | EIF4A3 (0.52) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL31273523 | 0.74 | EIF4A3 (0.66) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL3661193 | 0.74 | KDM4E (0.61) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL8828077 | 0.73 | KDM4E (0.58) | KDM4EALDH1A1GAAPOLBHSD17B10 | |
| SCHEMBL31423132 | 0.73 | KDM4E (0.44) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL5780183 | 0.71 | EIF4A3 (0.69) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| Acetone SCHEMBL4957341 | 0.71 | KDM4E (0.58) | EIF4A3KDM4EALDH1A1GAAPOLB | |
| SCHEMBL31422970 | 0.71 | KDM4E (0.42) | EIF4A3KDM4EALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119101045-A | Nitrogen-containing heterocyclic compounds, and preparation method and application thereof | 上海宇道生物技术有限公司 | 2024-12-10 | — | — | CN | disclosed |