Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31284851 | 0.93 | PDE4A (0.39) | CYP11B2ACACBPDE4APDE4BPDE4C | |
| SCHEMBL31284013 | 0.84 | CYP11B2 (0.37) | CYP11B2SCD5ACACBPDE4APDE4B | |
| SCHEMBL31283605 | 0.84 | CYP11B2 (0.41) | CYP11B2SCD5ACACBPIK3R1PIK3CA | |
| SCHEMBL31283570 | 0.84 | SYK (0.42) | CYP11B2SCD5ACACBPIK3R1PIK3CA | |
| SCHEMBL12879367 | 0.81 | GPR119 (0.41) | CYP11B2ACACBPOLBGPR119HDAC1 | |
| SCHEMBL12879359 | 0.81 | POLB (0.40) | CYP11B2ACACBPOLBGPR119 | |
| SCHEMBL31284125 | 0.81 | SCD5 (0.40) | CYP11B2SCD5RORCNR1H2USP30 | |
| SCHEMBL31283618 | 0.80 | ACACB (0.35) | CYP11B2SCD5ACACBPDE4APDE4B | |
| SCHEMBL2035683 | 0.78 | HPGD (0.38) | POLBUSP30GPR119 | |
| SCHEMBL31283733 | 0.78 | DGAT1 (0.43) | CYP11B2SCD5ACACBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731216-A1 | HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | Augustine Therapeutics (BE) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024261329-A1 | HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024261327-A1 | 2-(HETEROARYL-THIO)-1-(HETEROARYL)ETHANONE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2024-12-26 | — | — | WO | disclosed |