Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 3/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24454952 | 1.00 | MAPT (0.63) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL24454870 | 0.91 | RAB9A (0.60) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL2243229 | 0.84 | ALDH1A1 (0.71) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL2242824 | 0.83 | CASP3 (0.71) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL2607551 | 0.83 | NPC1 (0.75) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL13182114 | 0.82 | ALDH1A1 (0.69) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL24454908 | 0.77 | MAPT (0.57) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL31285581 | 0.77 | MAPT (0.57) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL24454923 | 0.76 | KDM4E (0.54) | MAPTKDM4ERAB9ANPC1MEN1 | |
| SCHEMBL2245490 | 0.76 | TP53 (0.69) | MAPTKDM4ERAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | claimed |
| EP-4247800-B1 | N-SUBSTITUTED 4-(1,3-ARYLOXAZOLO-2-YL)PHENYL COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN LA ROCHE (CH) | 2024-11-13 | — | — | EP | disclosed |