Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.69 |
| ▸ | HPGD | P15428 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.65 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.65 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607551 | 0.89 | NPC1 (0.75) | ALDH1A1KDM4EHPGDMAPTNPSR1 | |
| SCHEMBL2243229 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL2242824 | 0.87 | CASP3 (0.71) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL4082942 | 0.86 | ALDH1A1 (0.79) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL29479738 | 0.85 | ALDH1A1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL13182115 | 0.82 | MAPT (1.00) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL24454952 | 0.82 | MAPT (0.63) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL31284616 | 0.82 | MAPT (0.63) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL16942520 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL2242881 | 0.78 | MAPT (0.79) | ALDH1A1KDM4EHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150099781-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-09 | — | — | US | disclosed |
| US-8969342-B2 | Compounds and methods for treating mammalian gastrointestinal microbial infections | BRANDEIS UNIVERSITY (US) | 2015-03-03 | — | — | US | disclosed |
| WO-2010108187-A2 | COMPOUNDS AND METHODS FOR TREATING MAMMALIAN GASTROINTESTINAL MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099781-A1 | Compounds and Methods for Treating Mammalian Gastrointestinal Microbial Infections | IMPDH1, IMPDH2, IMPA1 | ALDH1A1 45/4885KDM4E 1620/4885HSD17B10 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.