Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123431 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2CA1CA2CA9CA14 | |
| SCHEMBL2224074 | 0.84 | ATM (0.61) | PLAAT3PLAAT5PLAAT2PLAAT4CA1 | |
| Water SCHEMBL11279881 | 0.82 | ATM (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4CA1 | |
| SCHEMBL3129382 | 0.82 | ALOX5 (0.47) | SMN1; SMN2CA1CA2CA9CA14 | |
| SCHEMBL3129954 | 0.81 | IGF1R (0.41) | LMNA | |
| SCHEMBL5723904 | 0.80 | CYP3A4 (0.64) | PLAAT3PLAAT5PLAAT2PLAAT4LMNA | |
| SCHEMBL9632482 | 0.80 | PKM (0.52) | SMN1; SMN2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL2221405 | 0.79 | KDM4E (0.59) | PLAAT3PLAAT5PLAAT2PLAAT4CA1 | |
| SCHEMBL3126685 | 0.78 | ALDH1A1 (0.49) | PLAAT3PLAAT5PLAAT2PLAAT4KDM4E | |
| SCHEMBL5192275 | 0.78 | KDM4E (0.57) | PLAAT3PLAAT5PLAAT2PLAAT4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036632-A1 | AZAINDAZOLE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |