SCHEMBL31290232

SCHEMBL31290232

Oc1c(Br)c(Br)cc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
PTPN22 Q9Y2R2 1/20 0.45
TRPM4 Q8TD43 1/20 0.45
ALDH1A1 P00352 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
HSD17B10 Q99714 1/20 0.44
NQO2 P16083 2/20 0.43
CASP6 P55212 1/20 0.43
NQO1 P15559 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886000 1.00 POLB (0.47) POLBPTPN22TRPM4ALDH1A1CA1
Cyanate SCHEMBL7106900 0.91 POLB (0.40) POLBPTPN22TRPM4ALDH1A1CA1
SCHEMBL6545417 0.84 CASP6 (0.48) POLBPTPN22TRPM4ALDH1A1CA1
SCHEMBL30023913 0.83 TRPM4 (0.56) POLBPTPN22TRPM4ALDH1A1HIF1A
SCHEMBL6600451 0.83 POLB (0.52) POLBPTPN22TRPM4ALDH1A1CA1
SCHEMBL10530767 0.83 NQO1 (0.50) POLBPTPN22TRPM4ALDH1A1HIF1A
SCHEMBL27984726 0.83 TRPM4 (0.56) POLBPTPN22TRPM4ALDH1A1HIF1A
SCHEMBL23155051 0.81 POLB (0.45) POLBPTPN22TRPM4ALDH1A1HIF1A
SCHEMBL5637840 0.79 ALDH1A1 (0.50) POLBTRPM4ALDH1A1HIF1ACYP1B1
SCHEMBL29518510 0.79 ALDH1A1 (0.50) POLBTRPM4ALDH1A1HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118932351-A Electrochemical tandem preparation and application of antibacterial compound 2-amino quinone 温州医科大学附属口腔医院 2024-11-12 CN claimed
CN-118932351-A Electrochemical tandem preparation and application of antibacterial compound 2-amino quinone 温州医科大学附属口腔医院 2024-11-12 CN disclosed