Sugi Predict

Sugi Predict / Compounds / Cyanate

Cyanate

Cyanate

SCHEMBL7106900

N#CO.Oc1c(Br)c(Br)cc2ccccc12

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ PTPN22 Q9Y2R2 1/20 0.38
▸ TRPM4 Q8TD43 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ CACNA1B Q00975 1/20 0.38
▸ APBA1 Q02410 1/20 0.38
▸ CA1 P00915 2/20 0.38
▸ CA2 P00918 2/20 0.38
▸ CA4 P22748 1/20 0.38
▸ CA6 P23280 1/20 0.38
▸ CASP6 P55212 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ CYP1B1 Q16678 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ NQO2 P16083 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886000 0.91 POLB (0.47) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL31290232 0.91 POLB (0.47) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL6545417 0.77 CASP6 (0.48) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL30023913 0.75 TRPM4 (0.56) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL27984726 0.75 TRPM4 (0.56) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL10530767 0.75 NQO1 (0.50) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL6600451 0.75 POLB (0.52) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL23155051 0.73 POLB (0.45) POLBALDH1A1MAPTMEN1KMT2A
SCHEMBL5637840 0.72 ALDH1A1 (0.50) POLBALDH1A1MEN1KMT2ATRPM4
SCHEMBL29518510 0.72 ALDH1A1 (0.50) POLBALDH1A1MEN1KMT2ATRPM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458993-B1 AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS VANTICO INC. 2002-10-01 — — US claimed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 — — US claimed
EP-1161414-B1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2003-10-01 — — EP disclosed
US-6458993-B1 AROMATIC CYANATE ESTER COMPOUNDS HAVING AT LEAST TWO RINGS LINKED BY AN UNSATURATED GROUP CONTAINING MEMBER CAN BE EMPLOYED IN ADHESIVES, COMPOSITES, LAMINATES AND MOLDINGS VANTICO INC. 2002-10-01 — — US disclosed
US-20020055648-A1 Cyanate esters having flame resistant properties JPMORGAN CHASE BANK, N.A. 2002-05-09 — — US disclosed
EP-1161414-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES Vantico AG (CH) 2001-12-12 — — EP disclosed
US-6242638-B1 FIREPROOFING USING CURED MIXTURES VANTICO INC. 2001-06-05 — — US disclosed
WO-2000055123-A1 CYANATE ESTERS HAVING FLAME RESISTANT PROPERTIES VANTICO AG (CH) 2000-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055648-A1 Cyanate esters having flame resistant properties PCCA, FABP4, MCCC2 POLB 2539/4885ALDH1A1 1536/4885MAPT 1030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.