Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 17/20 | 0.60 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.56 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3241375 | 0.91 | ROCK2 (0.68) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3246271 | 0.88 | ROCK2 (0.57) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3127171 | 0.87 | ROCK2 (0.74) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3247721 | 0.86 | ROCK2 (0.54) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL13391129 | 0.83 | ROCK2 (0.67) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3250349 | 0.81 | ROCK2 (0.63) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3241015 | 0.81 | ROCK2 (0.63) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3248059 | 0.80 | ROCK2 (0.57) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3124497 | 0.80 | ROCK2 (0.62) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL3241104 | 0.78 | ROCK2 (0.62) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |