SCHEMBL31290437

SCHEMBL31290437

COC(=O)CSC(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
RXFP1 Q9HBX9 2/20 0.45
HSD17B10 Q99714 2/20 0.45
MAPK1 P28482 2/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 2/20 0.45
USP2 O75604 1/20 0.45
PRNP P04156 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11445412 0.91 PTGS2 (0.47) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5022083 0.84 SLC6A3 (0.65) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL23215149 0.83 MMP8 (0.49) ALDH1A1KMT2ARXFP1TSHRPRNP
SCHEMBL31290475 0.83 CA12 (0.49) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL23215107 0.82 KMT2A (0.53) ALDH1A1SLC6A3KMT2AUSP2FFAR1
SCHEMBL29664591 0.82 KMT2A (0.53) ALDH1A1SLC6A3KMT2AUSP2FFAR1
SCHEMBL11455845 0.81 GRIA4 (0.48) ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A3
SCHEMBL11464626 0.81 GRIA4 (0.39) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11453748 0.80 HDAC3 (0.38) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL11464804 0.80 AKR1C3 (0.41) ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731739-A1 NEW COMPOUNDS Givaudan SA (CH) 2026-04-29 EP disclosed
WO-2024261201-A1 NEW COMPOUNDS GIVAUDAN SA (CH) 2024-12-26 WO disclosed