Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 5/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 17/20 | 0.46 |
| ▸ | ATF1 | P18846 | 13/20 | 0.46 |
| ▸ | JUN | P05412 | 5/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.44 |
| ▸ | RELA | Q04206 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481483 | 0.87 | NFKB1 (0.46) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL27471255 | 0.86 | NFKB1 (0.46) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL9564860 | 0.82 | XPO1 (0.34) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL2352670 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL9564908 | 0.78 | NFKB1 (0.63) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL11022702 | 0.78 | NFKB1 (0.37) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL3125746 | 0.76 | — | — | |
| SCHEMBL480176 | 0.75 | XPO1 (0.62) | XPO1NFKB1ATF1JUNNFKB2 | |
| SCHEMBL17644333 | 0.73 | MGLL (0.33) | — | |
| SCHEMBL9564867 | 0.72 | ATF1 (0.48) | XPO1NFKB1ATF1JUNNFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |