Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926455 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP3A4SRCKMT2ACYP2D6 | |
| SCHEMBL9342917 | 0.85 | ALDH1A1 (0.49) | ALDH1A1CYP3A4SRCKMT2ACYP2D6 | |
| SCHEMBL2485143 | 0.81 | KMT2A (0.58) | ALDH1A1CYP3A4KMT2AGAALMNA | |
| SCHEMBL16446497 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP3A4SRCKMT2ACYP2C19 | |
| SCHEMBL2488220 | 0.81 | KMT2A (0.58) | ALDH1A1CYP3A4KMT2AGAALMNA | |
| SCHEMBL384247 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2ACYP2C19GAA | |
| SCHEMBL29658783 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP3A4SRCKMT2ACYP2C19 | |
| Water SCHEMBL8819165 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP3A4SRCKMT2ACYP2C19 | |
| SCHEMBL16666455 | 0.79 | L3MBTL1 (0.54) | ALDH1A1CYP3A4SRCKMT2AGAA | |
| SCHEMBL1174285 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1CYP3A4KMT2ACYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4734989-A2 | SYNTHESIS AND IN VITRO CHARACTERIZATION OF PROTEOLYSIS TARGETING CHIMERAS (PROTACS) FOR DEGRADATION OF DNA METHYLTRANSFERASE 1 (DNMT1) | Dana-Farber Cancer Institute, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025006902-A2 | SYNTHESIS AND IN VITRO CHARACTERIZATION OF PROTEOLYSIS TARGETING CHIMERAS (PROTACS) FOR DEGRADATION OF DNA METHYLTRANSFERASE 1 (DNMT1) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-01-02 | — | — | WO | disclosed |