Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 3/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293254 | 0.91 | GPR119 (0.53) | DPP4GPR119SMN1; SMN2TP53YAP1 | |
| SCHEMBL31293137 | 0.88 | GPR119 (0.47) | DPP4GPR119SMN1; SMN2TP53YAP1 | |
| SCHEMBL30543873 | 0.87 | GPR119 (0.45) | DPP4GPR119FPR2P2RX7YAP1 | |
| SCHEMBL15954407 | 0.84 | DPP4 (0.51) | DPP4GPR119MAPK1FPR2 | |
| SCHEMBL27727638 | 0.84 | DPP4 (0.62) | DPP4GPR119MAPK1TP53FPR2 | |
| SCHEMBL25338945 | 0.83 | GPR119 (0.48) | DPP4GPR119FPR2YAP1MMP13 | |
| SCHEMBL17892096 | 0.83 | ALDH1A1 (0.48) | DPP4GPR119MAPK1SMN1; SMN2FPR2 | |
| SCHEMBL31293121 | 0.83 | YAP1 (0.42) | DPP4GPR119SMN1; SMN2TP53YAP1 | |
| SCHEMBL25171515 | 0.81 | GPR119 (0.48) | DPP4GPR119YAP1 | |
| SCHEMBL31169729 | 0.81 | GPR119 (0.48) | DPP4GPR119YAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747236-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | Eli Lilly and Company (US) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025024210-A1 | PIPERIDINE, MORPHOLINE AND TETRAHYDRO-PYRIDAZINE COMPOUNDS WITH LP(A) LOWERING ACTIVITY | ELI LILLY AND COMPANY (US) | 2025-01-30 | — | — | WO | disclosed |