Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 8/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293875 | 0.88 | EPHX2 (0.46) | UBE2MDCUN1D1EPHX2KMT2AALDH1A1 | |
| SCHEMBL31293858 | 0.87 | KMT2A (0.43) | SMN1; SMN2EPHX2KMT2AALDH1A1POLB | |
| SCHEMBL31293631 | 0.86 | EPHX2 (0.43) | EPHX2CCKBR | |
| SCHEMBL31294025 | 0.85 | SMN1; SMN2 (0.36) | UBE2MDCUN1D1SMN1; SMN2EPHX2CCKBR | |
| SCHEMBL31293519 | 0.83 | RAB9A (0.46) | SMN1; SMN2EPHX2CCKBRKMT2AALDH1A1 | |
| SCHEMBL31293410 | 0.83 | ENPP2 (0.35) | UBE2MDCUN1D1EPHX2KMT2AMEN1 | |
| SCHEMBL31293851 | 0.81 | SCN10A (0.35) | UBE2MDCUN1D1EPHX2KMT2AMEN1 | |
| SCHEMBL31293675 | 0.81 | CDK8 (0.43) | EPHX2 | |
| SCHEMBL31293478 | 0.78 | SYK (0.39) | EPHX2USP30 | |
| SCHEMBL31293611 | 0.77 | MEN1 (0.41) | SMN1; SMN2EPHX2KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |