Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 7/20 | 0.43 |
| ▸ | CCNC | P24863 | 6/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293664 | 0.89 | CDK8 (0.47) | CDK8CCNCRET | |
| SCHEMBL31293875 | 0.83 | EPHX2 (0.46) | CDK8EPHX2 | |
| SCHEMBL31293436 | 0.81 | UBE2M (0.35) | EPHX2 | |
| SCHEMBL31293851 | 0.80 | SCN10A (0.35) | EPHX2KDR | |
| SCHEMBL31293858 | 0.80 | KMT2A (0.43) | EPHX2 | |
| SCHEMBL31293631 | 0.79 | EPHX2 (0.43) | EPHX2KDR | |
| SCHEMBL31293410 | 0.79 | ENPP2 (0.35) | EPHX2 | |
| SCHEMBL31293883 | 0.78 | CDK8 (0.45) | CDK8CCNCEPHX2RETKDR | |
| SCHEMBL31293519 | 0.78 | RAB9A (0.46) | CDK8CCNCEPHX2 | |
| SCHEMBL31293478 | 0.77 | SYK (0.39) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |