Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 15/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293944 | 0.89 | KDR (0.37) | EPHX2KDR | |
| SCHEMBL31293970 | 0.87 | HCRTR2 (0.35) | EPHX2HCRTR1HCRTR2 | |
| SCHEMBL31293559 | 0.87 | USP30 (0.44) | SYKBTKHCRTR1HCRTR2 | |
| SCHEMBL31293908 | 0.87 | WNT1 (0.33) | EPHX2KDR | |
| SCHEMBL31293760 | 0.87 | SYK (0.40) | SYKBTK | |
| SCHEMBL31293777 | 0.86 | MAPK1 (0.36) | BTK | |
| SCHEMBL31293845 | 0.86 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL31293632 | 0.86 | SMARCA2 (0.39) | KDR | |
| SCHEMBL31293481 | 0.86 | CXCR3 (0.41) | EPHX2KDR | |
| SCHEMBL31293483 | 0.85 | SYK (0.35) | SYKHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | claimed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | claimed |