SCHEMBL31293682

SCHEMBL31293682

Cn1ccn2ncc(C(=O)N3CC4(CC(NC(=O)Nc5cnnc(C(F)(F)F)c5)C4)C3)c12

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31293632 0.88 SMARCA2 (0.39)
SCHEMBL31293571 0.87 EPHX2 (0.35) EPHX2
SCHEMBL31293618 0.85 MALT1 (0.35) EPHX2
SCHEMBL31293629 0.85 KDR (0.34) EPHX2
SCHEMBL31293599 0.85 CXCR3 (0.40) EPHX2
SCHEMBL31293845 0.85 EPHX2 (0.48) EPHX2
SCHEMBL31293696 0.84 EPHX2 (0.39) EPHX2
SCHEMBL31293490 0.84 EPHX2 (0.40) EPHX2
SCHEMBL31293908 0.84 WNT1 (0.33) EPHX2
SCHEMBL31293942 0.83 EPHX2 (0.31) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724439-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2026-04-15 EP disclosed
WO-2024251855-A1 HETEROARYL DERIVATIVES AS DDRS INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2024-12-12 WO disclosed