Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294000 | 0.87 | SMYD3 (0.44) | ENPP2ATXN2MEN1KMT2A | |
| SCHEMBL31293991 | 0.87 | EPHX2 (0.46) | MEN1KMT2A | |
| SCHEMBL31293957 | 0.84 | EPHX2 (0.43) | ENPP2ATXN2MEN1KMT2ATSHR | |
| SCHEMBL31293718 | 0.82 | KDR (0.41) | MEN1KMT2ATSHREPHB3 | |
| SCHEMBL31293453 | 0.80 | LMNA (0.42) | MEN1KMT2ATSHRNPSR1HSD17B10 | |
| SCHEMBL31293655 | 0.79 | POLB (0.47) | MEN1KMT2ATSHRTP53 | |
| SCHEMBL31293895 | 0.79 | CXCR3 (0.39) | ENPP2ATXN2EPHB3 | |
| SCHEMBL31293866 | 0.78 | KDR (0.39) | TSHRPAK1EPHB3 | |
| SCHEMBL31293523 | 0.77 | KDR (0.48) | MEN1KMT2ATP53 | |
| SCHEMBL31293965 | 0.75 | SPR (0.39) | ENPP2ATXN2HSD17B10EPHB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |