Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 8/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31293554 | 0.81 | SPR (0.39) | SPRRETPIK3CAMTORPARP1 | |
| SCHEMBL31293439 | 0.78 | EPHX2 (0.41) | EPHX2 | |
| SCHEMBL31293825 | 0.78 | EPHB3 (0.40) | SPREPHB3CHRNA7MGLLNAMPT | |
| SCHEMBL31293985 | 0.75 | ENPP2 (0.46) | EPHB3ENPP2ATXN2HSD17B10 | |
| SCHEMBL31294000 | 0.74 | SMYD3 (0.44) | RETNAMPTENPP2ATXN2 | |
| SCHEMBL31293895 | 0.74 | CXCR3 (0.39) | EPHB3ENPP2ATXN2 | |
| SCHEMBL31293718 | 0.74 | KDR (0.41) | EPHB3 | |
| SCHEMBL31293991 | 0.74 | EPHX2 (0.46) | EPHX2 | |
| SCHEMBL31293866 | 0.73 | KDR (0.39) | EPHB3EPHX2 | |
| SCHEMBL24011399 | 0.71 | NAMPT (0.46) | NAMPTENPP2ATXN2ALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724439-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024251855-A1 | HETEROARYL DERIVATIVES AS DDRS INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-12-12 | — | — | WO | disclosed |