Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 3/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136481 | 0.99 | PLA2G10 (0.48) | PLA2G10PLA2G2AMTNR1AMTNR1BANPEP | |
| SCHEMBL3141451 | 0.84 | ANPEP (0.42) | PLA2G10PLA2G2AMTNR1AMTNR1BANPEP | |
| SCHEMBL3131191 | 0.79 | ITGB3 (0.42) | — | |
| SCHEMBL6898811 | 0.75 | MTNR1A (0.48) | PLA2G10PLA2G2AMTNR1AMTNR1BFFAR1 | |
| SCHEMBL6898805 | 0.75 | MTNR1A (0.48) | PLA2G10PLA2G2AMTNR1AMTNR1BFFAR1 | |
| SCHEMBL22409416 | 0.73 | PLA2G10 (0.50) | PLA2G10PLA2G2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL22409417 | 0.73 | PLA2G10 (0.50) | PLA2G10PLA2G2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL3133004 | 0.70 | ITGB3 (0.44) | ALDH1A1 | |
| SCHEMBL13269905 | 0.69 | MAOA (0.38) | PLA2G10MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL26648108 | 0.69 | MTNR1A (0.50) | PLA2G10PLA2G2AMTNR1AMTNR1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079825-B1 | COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2010-07-21 | — | — | EP | disclosed |
| EP-1079825-A4 | COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | disclosed |
| EP-1079825-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6096773-A | INHIBITOR OF BINDING OF INTEGRIN TO ITS RECEPTORS, SUCH AS (VASCULAR CELL ADHESION MOLECULE-1) AND FIBRONECTIN AND USEFUL FOR CONTROLLING THE DISEASES INDUCED BY BINDING | TEXAS BIOTECHNOLOGY CORPORATION, INC. (US) | 2000-08-01 | — | — | US | disclosed |
| WO-1999052493-A2 | COMPOUNDS THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |