Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898805 | 1.00 | MTNR1A (0.48) | MTNR1AMTNR1BPLA2G10PLA2G2AMAOA | |
| SCHEMBL27538290 | 0.85 | MTNR1A (0.42) | MTNR1AMTNR1BPLA2G10NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6899201 | 0.83 | MAOA (0.44) | MTNR1AMTNR1BPLA2G10MAOAMAOB | |
| Hydrochloric Acid SCHEMBL6899197 | 0.83 | MAOA (0.44) | MTNR1AMTNR1BPLA2G10MAOAMAOB | |
| SCHEMBL3129444 | 0.75 | PLA2G10 (0.49) | MTNR1AMTNR1BPLA2G10PLA2G2AFFAR1 | |
| Hydrochloric Acid SCHEMBL6898788 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BMAOAMAOBNPC1 | |
| Hydrochloric Acid SCHEMBL6898792 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BMAOAMAOBNPC1 | |
| SCHEMBL3136481 | 0.74 | PLA2G10 (0.48) | MTNR1AMTNR1BPLA2G10PLA2G2AFFAR1 | |
| SCHEMBL9645538 | 0.74 | PLA2G10 (0.59) | MTNR1AMTNR1BPLA2G10PLA2G2AFFAR1 | |
| SCHEMBL22428825 | 0.72 | MAOA (0.45) | MTNR1AMTNR1BMAOAMAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730784-B2 | AS THERAPEUTIC AGENTS FOR AUTOIMMUNE DISEASES SUCH AS RHEUMATOID ARTHRITIS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-20020198376-A1 | Novel urea derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-26 | — | — | US | disclosed |
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1072591-A1 | NOVEL UREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198376-A1 | Novel urea derivatives | TNF, CTH, CFH | MTNR1A 1511/4885MTNR1B 1529/4885PLA2G10 4745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.