Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PDE1A | P54750 | 3/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827018 | 0.86 | HPGD (0.57) | HPGDKMT2AMEN1CYP3A4GSK3A | |
| SCHEMBL31213524 | 0.83 | HPGD (0.51) | HPGDADORA3ADORA1KMT2AMEN1 | |
| SCHEMBL31213514 | 0.81 | P2RX3 (0.48) | HPGDBRD4KMT2AMEN1CYP3A4 | |
| SCHEMBL31213513 | 0.81 | HPGD (0.52) | HPGDADORA3ADORA1KMT2AMEN1 | |
| SCHEMBL25827062 | 0.78 | CYP3A4 (0.69) | HPGDADORA3KMT2AMEN1CYP3A4 | |
| SCHEMBL320830 | 0.77 | RGS4 (0.53) | HPGDADORA3KMT2AMEN1TSHR | |
| SCHEMBL7847653 | 0.73 | HPGD (0.51) | HPGDKMT2AMEN1CYP3A4GSK3A | |
| SCHEMBL8985073 | 0.73 | GSK3B (0.67) | HPGDKMT2AMEN1CYP3A4GSK3A | |
| SCHEMBL10159514 | 0.72 | MAPT (0.49) | HPGDKMT2AMEN1CYP3A4GSK3A | |
| SCHEMBL25129867 | 0.71 | P2RX3 (0.66) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118931-A | Barbituric acid derivative and preparation method thereof | 武汉绿合医药科技有限公司 | 2024-12-13 | — | — | CN | disclosed |