Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31213524 | 0.90 | HPGD (0.51) | HPGDKDM4EALDH1A1KDM4ATSHR | |
| SCHEMBL31213513 | 0.87 | HPGD (0.52) | HPGDKMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL320830 | 0.87 | RGS4 (0.53) | HPGDKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL7847653 | 0.86 | HPGD (0.51) | HPGDKDM4EALDH1A1KDM4ATSHR | |
| SCHEMBL31295481 | 0.86 | HPGD (0.48) | HPGDKDM4EALDH1A1KDM4ATSHR | |
| SCHEMBL25827062 | 0.84 | CYP3A4 (0.69) | HPGDKDM4EALDH1A1KDM4ATSHR | |
| SCHEMBL25827237 | 0.82 | GABRA5 (0.48) | KMT2AMEN1CYP3A4 | |
| SCHEMBL8985073 | 0.82 | GSK3B (0.67) | HPGDKDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10159514 | 0.81 | MAPT (0.49) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL31213514 | 0.80 | P2RX3 (0.48) | HPGDKMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |