SCHEMBL31296496

SCHEMBL31296496

COC(=O)C1(C(=O)OC)Cc2c(C)cc(C3CCCCC3)c(C)c2C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 5/20 0.35
PTGDR Q13258 2/20 0.35
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
TAS1R2 Q8TE23 2/20 0.34
PSMB5 P28074 1/20 0.32
USP2 O75604 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
SLC6A3 Q01959 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
PDK2 Q15119 1/20 0.31
PDK4 Q16654 1/20 0.31
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
JAK2 O60674 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31296499 0.93 SLC6A3 (0.36) SLC6A3PDK2PDK4
SCHEMBL31296464 0.78 CA12 (0.32) POLBSLC6A3
SCHEMBL23857599 0.76 MT-CO2 (0.35) LMNAPOLBPDK2PDK4TSHR
SCHEMBL30253323 0.75 MT-CO2 (0.34) LMNAPOLBPDK2PDK4TSHR
SCHEMBL31296432 0.72 LMNA (0.33) LMNAPOLBTSHR
SCHEMBL31296468 0.71 MEN1 (0.36) ALDH1A1LMNAPOLBMEN1KMT2A
SCHEMBL31296467 0.71 KDM4E (0.38) ALDH1A1POLBCYP1A2
SCHEMBL23857275 0.70 UCHL1 (0.30)
SCHEMBL31296486 0.70
SCHEMBL30253200 0.70 UCHL1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219681-A Method for synthesizing axial chiral organoboron compounds 合成化学暨分子生物学有限公司 2024-12-31 CN disclosed