Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TPMT | P51580 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999624 | 1.00 | ACLY (0.53) | ACLYALDH1A1KDM4ETPMTGAA | |
| SCHEMBL31573792 | 0.83 | ACLY (0.46) | ACLYALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL31573632 | 0.83 | TPMT (0.46) | ACLYALDH1A1KDM4ETPMTGAA | |
| SCHEMBL2391150 | 0.83 | ALDH1A1 (0.65) | ACLYALDH1A1KDM4ETPMTGAA | |
| SCHEMBL31573339 | 0.80 | NOTUM (0.44) | ACLYALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL3164592 | 0.78 | ALDH1A1 (0.54) | ACLYALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL1495720 | 0.78 | ALDH1A1 (0.65) | ACLYALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL29948709 | 0.78 | ALDH1A1 (0.54) | ACLYALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL24481314 | 0.77 | ALDH1A1 (0.53) | ACLYALDH1A1KDM4ETPMTGAA | |
| SCHEMBL5783293 | 0.76 | TRPV4 (0.49) | ACLYALDH1A1KDM4EL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119137107-A | Macrocyclic inhibitors of ATP citrate lyase | 艾斯柏伦治疗公司 | 2024-12-13 | — | — | CN | disclosed |