Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127864 | 0.84 | HRH4 (0.41) | HRH4PDE4BMEN1LMNAMAPT | |
| SCHEMBL3128993 | 0.82 | HRH4 (0.39) | HRH4RAB9ATRPM8MEN1LMNA | |
| SCHEMBL3205713 | 0.81 | HRH4 (0.38) | HRH4RAB9APDE4BTRPM8MEN1 | |
| SCHEMBL3211858 | 0.81 | HRH4 (0.40) | HRH4RAB9APDE4BTRPM8MEN1 | |
| SCHEMBL3125660 | 0.81 | RXRA (0.42) | HRH4RAB9ATRPM8MEN1LMNA | |
| SCHEMBL3218633 | 0.79 | HRH4 (0.37) | HRH4RAB9APDE4BTRPM8MEN1 | |
| SCHEMBL3201201 | 0.79 | HRH4 (0.36) | HRH4RAB9ATRPM8MEN1LMNA | |
| SCHEMBL3125802 | 0.77 | RAB9A (0.39) | HRH4RAB9APDE4BTRPM8MEN1 | |
| SCHEMBL3192323 | 0.76 | HRH4 (0.33) | HRH4PDE4B | |
| SCHEMBL3201858 | 0.75 | HRH4 (0.35) | HRH4TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |