Butenone

Butenone

SCHEMBL312972

CC(=O)C=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 1.00
GLA P06280 1/20 1.00
MAPT P10636 5/20 0.67
LMNA P02545 3/20 0.67
HDAC3 O15379 2/20 0.67
HDAC4 P56524 2/20 0.67
HDAC1 Q13547 2/20 0.67
HDAC2 Q92769 2/20 0.67
HDAC8 Q9BY41 2/20 0.67
HDAC6 Q9UBN7 2/20 0.67
PLIN1 O60240 2/20 0.67
RECQL P46063 2/20 0.67
PLIN5 Q00G26 2/20 0.67
ABHD5 Q8WTS1 2/20 0.67
ALDH1A1 P00352 2/20 0.67
F3 P13726 2/20 0.67
TNKS O95271 1/20 0.67
HCAR2 Q8TDS4 1/20 0.67
HDAC7 Q8WUI4 1/20 0.67
HDAC10 Q969S8 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butenone SCHEMBL12984182 1.00 TDP1 (1.00) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL76632 1.00 TDP1 (1.00) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL699144 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL7053850 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL6401376 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL6235457 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL14763524 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL792625 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL4306181 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3
Butenone SCHEMBL29184841 0.98 TDP1 (0.95) TDP1GLAMAPTLMNAHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6240 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748978-A1 DISPERSION ELECTROLYTE FOR TIN-NICKEL ALLOY LAYERS CONTAINING GRAPHITE PARTICLES Dr.Ing. Max Schlötter GmbH & Co. KG (DE) 2026-05-27 EP claimed
CN-117802460-B Polyimide composite film and preparation method thereof Shenzhen Ruiren New Material Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
EP-4731727-A1 HALF-WAVE PLATE Merck Patent GmbH (DE) 2026-04-29 EP claimed
EP-4713413-A1 CHIRAL REACTIVE MESOGEN MIXTURE Merck Patent GmbH (DE) 2026-03-25 EP claimed
EP-4713414-A1 OPTICAL ELEMENT COMPRISING A CHIRAL LC POLYMER FILM Merck Patent GmbH (DE) 2026-03-25 EP claimed
CN-121586757-A Half wave plate 默克专利股份有限公司 2026-02-27 CN claimed
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2026-01-29 US claimed
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 US claimed
EP-4464687-B1 PROCESS FOR THE PREPARATION OF AN ACETAL FROM AN OLEFIN USING AN IODINE ALKYL COMPOUND EVONIK OXENO GMBH & CO KG (DE) 2025-07-09 EP claimed
CN-119776927-B Tin-silver alloy electroplating solution and preparation method and application thereof 深圳市联合蓝海应用材料科技股份有限公司 2025-06-24 CN claimed
US-4170609-A Aldol condensation process TURNER WILLIAM F 1979-10-09 US claimed
US-4146441-A Additive compositions, baths, and methods for electrodepositing bright zinc deposits R. O. HULL & COMPANY, INC. (US) 1979-03-27 US claimed
US-4093523-A POTASSIUM CHLORIDE, BORIC ACID, AROMATIC ALDEHYDE OR KETONE IN A WETTING AGENT SYSTEM OF A FATTY IMIDAZOLE SULFONATE, A FATTY AMIDO BETAINE AND HYDROTROPE Wild, Edward B. (US) 1978-06-06 US claimed
US-4089755-A CATIONIC QUATERNARY AMMONIUM SURFACTANT THE RICHARDSON COMPANY (US) 1978-05-16 US claimed
US-4075066-A Electroplating zinc, ammonia-free acid zinc plating bath therefor and additive composition therefor R. O. HULL & COMPANY, INC. (US) 1978-02-21 US claimed
US-4056665-A Composition and process OWENS-ILLINOIS, INC. (US) 1977-11-01 US claimed
US-4049510-A AMINE POLYMER AND A PROPYLENE OXIDE-ETHYLENE OXIDE BLOCK COPOLYMER ION COLUMBIA CHEMICAL CORPORATION (US) 1977-09-20 US claimed
US-4014761-A ZINC SULFIDE, CHLORIDE, OR SULFAMATE M & T CHEMICALS INC. (US) 1977-03-29 US claimed
US-4007098-A USING THE REACTION PRODUCT OF A LINEAR AMINE POLYMER AND AN EPIHALOHYDRIN COLUMBIA CHEMICAL CORPORATION (US) 1977-02-08 US claimed
US-3988219-A Baths and additives for the electrodeposition of bright zinc COLUMBIA CHEMICAL CORPORATION (US) 1976-10-26 US claimed