Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | GLA | P06280 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.64 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.64 |
| ▸ | F3 | P13726 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butenone SCHEMBL792625 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL490740 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL2891566 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL5788285 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL29739250 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL4306181 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL7053850 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL6401376 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL12984182 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL76632 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899193-A | Preparation method based on diaryl carbazole material | 西北工业大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119638984-A | Polyaramid hole transport material, synthesis method thereof and perovskite solar cell | 浙江大学 | 2025-03-18 | — | — | CN | claimed |
| CN-119409614-A | Difluoromethyl heteroarene compound and preparation method thereof | 国网安徽省电力有限公司电力科学研究院 | 2025-02-11 | — | — | CN | claimed |
| CN-115246789-B | Preparation method of nodestrat | 上海医药集团青岛国风药业股份有限公司 | 2023-10-17 | — | — | CN | claimed |
| CN-112679429-B | Method for preparing isoquinolinones compound | 上海迪赛诺化学制药有限公司 | 2023-05-05 | — | — | CN | claimed |
| US-20230112619-A1 | METHOD FOR PREPARING ISOQUINOLINONE COMPOUNDS | ARIZEST (SHANGHAI) PHARMATECH CO., LTD. (CN) | 2023-04-13 | — | — | US | claimed |
| CN-115246789-A | Preparation method of nodispat | 上海医药集团青岛国风药业股份有限公司 | 2022-10-28 | — | — | CN | claimed |
| CN-110272386-B | Preparation method of nodispat | 上海医药集团青岛国风药业股份有限公司 | 2022-09-09 | — | — | CN | claimed |
| WO-2019174631-A1 | METHOD FOR PREPARING NORSTAT | 上海医药集团股份有限公司 | 2019-09-19 | — | — | WO | claimed |
| EP-4051667-B1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | LILAC THERAPEUTICS INC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-11-06 | — | — | US | disclosed |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | MAXYMUNE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | Maxymune Therapeutics, Inc. (US) | 2025-09-30 | — | — | US | disclosed |
| US-20250206974-A1 | ELECTRO-OPTIC INK COMPOSITION, COMPOUND, ELECTRO-OPTIC FILM, AND ELECTRO-OPTIC ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2025-06-26 | — | — | US | disclosed |
| US-6057335-A | Pyrazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| US-5990346-A | AN INHIBITORS OF CELL MIGRATION CAUSED BY CHEMOKINES | TEIJIN LIMITED (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0945439-A1 | NOVEL AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0945440-A1 | AMINOPYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0945438-A1 | PYRAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0778269-A1 | PROSTAGLANDINS AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1997-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250339388-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | TDP1 1176/4885GLA 4414/4885MAPT 858/4885 |
| US-20230112619-A1 | METHOD FOR PREPARING ISOQUINOLINONE COMPOUNDS | SQLE, PDE8B, PDE8A | TDP1 1632/4885GLA 2402/4885MAPT 2281/4885 |
| US-12427124-B1 | Phenylalanine-based LAT1 inhibitors and uses thereof | SLC43A1, SLC7A1, SLC1A5 | TDP1 1176/4885GLA 4414/4885MAPT 858/4885 |
| US-20250319046-A1 | PHENYLALANINE-BASED LAT1 INHIBITORS AND USES THEREOF | SLC43A1, SLC7A1, SLC1A5 | TDP1 1176/4885GLA 4414/4885MAPT 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.