Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | GLA | P06280 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.64 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.64 |
| ▸ | F3 | P13726 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butenone SCHEMBL792625 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL490740 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL2891566 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL5788285 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL699144 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL29739250 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL4306181 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL6401376 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL12984182 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL76632 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116997575-A | Polymer and application thereof | 日产化学株式会社 | 2023-11-03 | — | — | CN | disclosed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-29 | — | — | US | disclosed |
| CN-114929676-A | Heterocyclic carboxylate compounds as glycolate oxidase inhibitors | 紫丁香疗法有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-110437046-B | Fluorine atom-containing polymer and field of use thereof | 日产化学工业株式会社 | 2022-08-16 | — | — | CN | disclosed |
| CN-109563243-B | Fluorine atom-containing polymer and use thereof | 日产化学株式会社 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021073623-A1 | METHOD FOR PREPARING ISOQUINOLINONE COMPOUNDS | 上海迪赛诺化学制药有限公司 | 2021-04-22 | — | — | WO | disclosed |
| WO-2003024975-A1 | LAULIMALIDE-DERIVATIVES, THEIR USE AND PROCESS FOR THE PRODUCTION OF LAULIMALIDE AND LAULIMALIDE-DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142119-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | TDP1 361/4885GLA 1496/4885MAPT 68/4885 |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | TDP1 361/4885GLA 1496/4885MAPT 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.