Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.95 |
| ▸ | GLA | P06280 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.64 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.64 |
| ▸ | F3 | P13726 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butenone SCHEMBL792625 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL490740 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL2891566 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL5788285 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL699144 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL29739250 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL7053850 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL6401376 | 1.00 | TDP1 (0.95) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL12984182 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 | |
| Butenone SCHEMBL76632 | 0.98 | TDP1 (1.00) | TDP1GLAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109261209-A | It is a kind of using nitrogen heterocycle carbine ligand as the preparation method of the monatomic catalyst of carrier | 广西师范大学 | 2019-01-25 | — | — | CN | claimed |
| CN-102453051-B | Synthesizing method of axis-unfixed biphenyl phosphine-oxazoline chiral ligand | UNIV SHANGHAI JIAOTONG | 2014-12-24 | — | — | CN | claimed |
| CN-102453051-A | Synthesis method of axis-unstable biphenyl phosphine-oxazoline chiral ligand | UNIV SHANGHAI JIAOTONG | 2012-05-16 | — | — | CN | claimed |
| EP-1270582-B1 | TRIPHENYLPHOSPHINE DERIVATIVES, PALLADIUM OR NICKEL COMPLEXES THEREOF, AND PROCESS FOR PREPARING BIARYL DERIVATIVES | MITSUBISHI RAYON CO (JP) | 2006-08-30 | — | — | EP | claimed |
| US-6693210-B2 | USING PALLADIUM, NICKEL PHOSPHINE COMPLEX AS CATALYSTS | MITSUBISHI RAYON CO., LTD. (JP) | 2004-02-17 | — | — | US | claimed |
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | MITSUBISHI RAYON CO., LTD. (JP) | 2003-04-03 | — | — | US | claimed |
| EP-1270582-A1 | TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE | Mitsubishi Rayon Co., Ltd. (JP) | 2003-01-02 | — | — | EP | claimed |
| JP-3068533-A | — | — | None | — | — | JP | disclosed |
| WO-2019190241-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2019-10-03 | — | — | WO | disclosed |
| WO-2019164218-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | 주식회사 엘지화학 | 2019-08-29 | — | — | WO | disclosed |
| CN-109261209-A | It is a kind of using nitrogen heterocycle carbine ligand as the preparation method of the monatomic catalyst of carrier | 广西师范大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-102453051-B | Synthesizing method of axis-unfixed biphenyl phosphine-oxazoline chiral ligand | UNIV SHANGHAI JIAOTONG | 2014-12-24 | — | — | CN | disclosed |
| US-8697824-B2 | Cross-linkable bi-sulphonyl derivatives and their uses for preparing ion-exchanging membranes | HYDRO QUEBEC (CA) | 2014-04-15 | — | — | US | disclosed |
| EP-1270582-A1 | TRIPHENYLPHOSPHINE DERIVATIVE, PRODUCTION PROCESS THEREFOR, PALLADIUM COMPLEX THEREOF, AND PROCESS FOR PRODUCING BIARYL DERIVATIVE | Mitsubishi Rayon Co., Ltd. (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-0973734-A1 | CROSSLINKABLE BI-SULPHONYL DERIVATIVES AND THEIR USES FOR PREPARING ION-EXCHANGING MEMBRANES | HYDRO-QUEBEC (CA) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999038842-A1 | CROSSLINKABLE BI-SULPHONYL DERIVATIVES AND THEIR USES FOR PREPARING ION-EXCHANGING MEMBRANES | HYDRO-QUEBEC (CA) | 1999-08-05 | — | — | WO | disclosed |
| EP-0323141-B1 | Preparation of cinnamate esters | MITSUI TOATSU CHEMICALS (JP) | 1994-03-16 | — | — | EP | disclosed |
| JP-H0368533-A | PRODUCTION OF DIARYL KETONE | SAGAMI CHEM RES CENTER | 1991-03-25 | — | — | JP | disclosed |
| US-4908472-A | Preparation process of cinnamate ester | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0323141-A2 | Preparation of cinnamate esters | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065208-A1 | Using palladium, nickel phosphine complex as catalysts | PDCD1LG2, PIK3CA, PDCD1 | TDP1 4088/4885GLA 4030/4885MAPT 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.