Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 8/20 | 0.34 |
| ▸ | CA1 | P00915 | 7/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470118 | 0.86 | CA2 (0.44) | CTSBCA2CA1CA9CA12 | |
| SCHEMBL3811042 | 0.79 | CA1 (0.42) | CTSBCA2CA1CA9CA12 | |
| SCHEMBL8078639 | 0.79 | MYC (0.40) | CTSBHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL6019444 | 0.71 | CA1 (0.41) | CTSBCA2CA1CA9CA12 | |
| SCHEMBL20680983 | 0.70 | CA2 (0.40) | SLC6A4CA2CA1CA9CA12 | |
| SCHEMBL6019475 | 0.68 | EED (0.50) | KMT2A | |
| SCHEMBL31297330 | 0.68 | PTGES2 (0.35) | CA2CA1CA9CA4CA6 | |
| SCHEMBL2051705 | 0.67 | HSPA5 (0.52) | CA2CA9CA12 | |
| SCHEMBL1722278 | 0.67 | CYP3A4 (0.39) | SLC6A4HTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL21962272 | 0.67 | CYP2A13 (0.53) | CTSBCA2MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240382474-A1 | ENPP1 MODULATORS AND USES THEREOF | VIR BIOTECHNOLOGY INC (US) | 2024-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382474-A1 | ENPP1 MODULATORS AND USES THEREOF | ENPP1, ENPP2, ENPP3 | SLC6A4 2946/4885CTSB 2784/4885HTR1A 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.