Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28197978 | 0.88 | LMNA (0.55) | LMNASLC15A2EGLN1CA1ALKBH5 | |
| Succinic Acid SCHEMBL6906103 | 0.86 | LMNA (0.69) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27518008 | 0.86 | LMNA (0.69) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Butyric Acid SCHEMBL31606801 | 0.85 | FFAR3 (0.72) | CA1OR51E2FFAR3HDAC3HDAC1 | |
| Beta-Alanine SCHEMBL27522329 | 0.83 | LMNA (0.48) | LMNASLC15A2EGLN1CA1ALKBH5 | |
| Succinic Acid SCHEMBL10385827 | 0.83 | LMNA (0.64) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL17975779 | 0.82 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL2148509 | 0.82 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL16415716 | 0.82 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL35204 | 0.82 | EGLN1 (0.75) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117129538-A | Electrochemical beta-hydroxybutyric acid test strip and manufacturing method thereof | 掌护智慧医疗(深圳)有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-114097794-A | Synergistic composition containing pyrazole amide compounds | 山东省联合农药工业有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-1679508-B1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | ARKRAY INC (JP) | 2010-07-21 | — | — | EP | claimed |
| CN-100456032-C | Biosensor and method for manufacturing the same | ARKRAY INC (JP) | 2009-01-28 | — | — | CN | claimed |
| US-20070034512-A1 | Biosensor and method for producing the same | ARKRAY, INC. (JP) | 2007-02-15 | — | — | US | claimed |
| CN-1875265-A | Biosensor and method for manufacturing the same | ARKRAY INC (JP) | 2006-12-06 | — | — | CN | claimed |
| EP-1679508-A1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | Arkray, Inc. (JP) | 2006-07-12 | — | — | EP | claimed |
| EP-3301183-B1 | BIOSENSOR, PRODUCTION METHOD THEREOF, AND METHOD AND SYSTEM FOR MEASURING GLUCOSE OR LACTATE | ARKRAY INC (JP) | 2024-05-08 | — | — | EP | disclosed |
| EP-3477290-B1 | ELECTRODE AND METHOD FOR MEASURING ASCORBIC ACID | ARKRAY INC (JP) | 2024-01-03 | — | — | EP | disclosed |
| CN-117129538-A | Electrochemical beta-hydroxybutyric acid test strip and manufacturing method thereof | 掌护智慧医疗(深圳)有限公司 | 2023-11-28 | — | — | CN | disclosed |
| US-20230341347-A1 | BIOSENSOR | ARKRAY, INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230338945-A1 | BIOSENSOR AND METHOD OF MANUFACTURING BIOSENSOR | ARKRAY, INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| EP-4266037-A1 | BIOSENSOR AND METHOD FOR MANUFACTURING BIOSENSOR | ARKRAY, Inc. (JP) | 2023-10-25 | — | — | EP | disclosed |
| EP-2573191-A1 | Glucose sensor | ARKRAY, Inc. (JP) | 2013-03-27 | — | — | EP | disclosed |
| EP-1679508-B1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | ARKRAY INC (JP) | 2010-07-21 | — | — | EP | disclosed |
| CN-100456032-C | Biosensor and method for manufacturing the same | ARKRAY INC (JP) | 2009-01-28 | — | — | CN | disclosed |
| US-20070034512-A1 | Biosensor and method for producing the same | ARKRAY, INC. (JP) | 2007-02-15 | — | — | US | disclosed |
| CN-1875265-A | Biosensor and method for manufacturing the same | ARKRAY INC (JP) | 2006-12-06 | — | — | CN | disclosed |
| EP-1679508-A1 | BIOSENSOR AND METHOD FOR PREPARATION THEREOF | Arkray, Inc. (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-1251184-A1 | REACTION METHOD, REACTION APPARATUS AND ENZYME | Kabushiki Kaisha Toyota Chuo Kenkyusho (JP) | 2002-10-23 | — | — | EP | disclosed |