Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 7/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297591 | 0.80 | CYP17A1 (0.35) | KDM4EPTK2CYP17A1 | |
| SCHEMBL31297675 | 0.79 | TGFBR1 (0.39) | PIK3CAPIK3CDPTK2EPHB4 | |
| SCHEMBL31297707 | 0.77 | MET (0.44) | PIK3CAPIK3CDTDO2MAPK10CDK8 | |
| SCHEMBL31297654 | 0.76 | — | — | |
| SCHEMBL31297547 | 0.73 | MAPT (0.45) | PIK3CAPIK3CDKDM4ECYP17A1CDK8 | |
| SCHEMBL31297689 | 0.72 | ADORA2B (0.42) | EPHB4MAP4K4DYRK1A | |
| SCHEMBL31297703 | 0.72 | EPHB4 (0.36) | TDO2PTK2EPHB4MAP4K4CDK8 | |
| SCHEMBL31297671 | 0.71 | ALDH1A1 (0.43) | KDM4ECYP17A1EPHB4 | |
| SCHEMBL8644295 | 0.71 | PIK3CA (0.73) | FGFR4PIK3CAPIK3CDTDO2EGFR | |
| SCHEMBL31297616 | 0.70 | CYP2A6 (0.49) | KDM4EPTK2CDK5DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735114-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025002491-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | MASARYKOVA UNIVERZITA (CZ) | 2025-01-02 | — | — | WO | disclosed |
| EP-4483954-A1 | SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES | Masarykova Univerzita (CZ) | 2025-01-01 | — | — | EP | disclosed |