SCHEMBL3129798

SCHEMBL3129798

CCC=C(C)C(=O)ON1CCOCC1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 4/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 3/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
RECQL P46063 2/20 0.36
HTT P42858 2/20 0.35
POLB P06746 3/20 0.34
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
FKBP1A P62942 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10772361 1.00 TSHR (0.39) TSHRALDH1A1GAALMNARAB9A
SCHEMBL2311241 0.90 ALDH1A1 (0.33) TSHRALDH1A1GAALMNARAB9A
SCHEMBL1537185 0.88
SCHEMBL27845255 0.87 TSHR (0.37) TSHRALDH1A1GAALMNARAB9A
SCHEMBL1085785 0.84
SCHEMBL5951186 0.84 L3MBTL1 (0.35) TSHRALDH1A1GAALMNARAB9A
SCHEMBL1086381 0.83 PSMB1 (0.31) KMT2AL3MBTL1
SCHEMBL9422144 0.83 SMN1; SMN2 (0.33) TSHRALDH1A1GAALMNARAB9A
SCHEMBL3335816 0.82 SMN1; SMN2 (0.41) TSHRALDH1A1GAALMNARAB9A
SCHEMBL14336051 0.80 SIGMAR1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107493684-B Photocurable composition 三键有限公司 2019-08-30 CN claimed
CN-109464657-A A kind of method that block copolymer carries insulin control release 常州工程职业技术学院 2019-03-15 CN claimed
CN-106170502-B water-soluble cross-linked block copolymer 凯米拉公司 2018-11-16 CN claimed
CN-106170502-A Water-soluble cross-linked block copolymer 凯米拉公司 2016-11-30 CN claimed
CN-105026638-A Vane arrangement having alternating vanes with different trailing edge profile ELLIOTT CO 2015-11-04 CN claimed
EP-2906242-A1 DELIVERY OF SMALL INTERFERING RNA AND MICRO RNA THROUGH MEMBRANE-DISRUPTIVE, RESPONSIVE NANOSCALLE HYDROGELS Board Of Regents, The University Of Texas System (US) 2015-08-19 EP claimed
US-20150216814-A1 DELIVERY OF SMALL INTERFERING RNA AND MICRO RNA THROUGH MEMBRANE-DISRUPTIVE, RESPONSIVE NANOSCALLE HYDROGELS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2015-08-06 US claimed
CN-101061207-B Oil composition for lubricating an EGR equipped diesel engine and an EGR equipped diesel engine comprising same EVONIK ROHMAX ADDITIVES GMBH 2013-08-14 CN claimed
CN-1744815-B Particulate suspensions SYNGENTA LTD 2013-04-17 CN claimed
CN-102387779-A Ethylene copolymer with PEG, cationic and anionic units, cosmetic composition including same and treatment method OREAL 2012-03-21 CN claimed
CN-1103786-C High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide PHARMACIA IOVISION INC (US) 2003-03-26 CN claimed
CN-1300283-A Polymerizable hydrophilio ultraviolet light absorbing manomers PHARMACIA & UPJOHN BV (NL) 2001-06-20 CN claimed
CN-1052014-C Waterborne core-shell latex polymers MINNESOTA MINING & MFG (US) 2000-05-03 CN claimed
CN-1219179-A High refractive index hydrogels prepared from polymers and copolymers of N-benzyl-N-methylacrylamide PHARMACIA IOVISION INC (US) 1999-06-09 CN claimed
EP-0183027-B1 Biologically compatible adhesive DENTSPLY INT INC (US) 1994-07-13 EP claimed
US-4816495-A UNSATURATED PHOSPHATES AS ADHESION PROMOTERS DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1989-03-28 US claimed
EP-0226542-A2 Holograms ILFORD Limited (GB) 1987-06-24 EP claimed
EP-0225853-A2 Holograms ILFORD Limited (GB) 1987-06-16 EP claimed
US-4657941-A USED IN DENTISTRY DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1987-04-14 US claimed
EP-0183027-A2 Biologically compatible adhesive DENTSPLY INTERNATIONAL, INC. (US) 1986-06-04 EP claimed