Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ILK | Q13418 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31299670 | 0.80 | GAA (0.36) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL31299616 | 0.79 | TSHR (0.53) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL2211256 | 0.73 | MAPT (0.54) | TSHRILKALDH1A1CYP1A2POLB | |
| SCHEMBL22263170 | 0.71 | TSHR (0.44) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL4950787 | 0.71 | TSHR (0.44) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL28812803 | 0.71 | TSHR (0.44) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL1434485 | 0.71 | TSHR (0.44) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL7516781 | 0.70 | TSHR (0.58) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL27969503 | 0.70 | TSHR (0.46) | TSHRILKALDH1A1CYP1A2KDM4E | |
| SCHEMBL7794327 | 0.70 | TSHR (0.61) | TSHRILKALDH1A1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735426-A1 | HETEROAROMATIC DHODH INHIBITORS | Immunic AG (DE) | 2026-05-06 | — | — | EP | disclosed |
| WO-2025003402-A1 | HETEROAROMATIC DHODH INHIBITORS | IMMUNIC AG (DE) | 2025-01-02 | — | — | WO | disclosed |