SCHEMBL31301340

SCHEMBL31301340

CC(C)N(C(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)n1)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 6/20 0.43
SCN2A Q99250 4/20 0.43
GPBAR1 Q8TDU6 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
KDM1A O60341 1/20 0.37
KLRK1 P26718 1/20 0.36
MICA Q29983 1/20 0.36
RAET1L Q5VY80 1/20 0.36
CYP19A1 P11511 1/20 0.36
LTC4S Q16873 1/20 0.36
ALOX5 P09917 1/20 0.35
GCGR P47871 2/20 0.35
GIPR P48546 2/20 0.35
SCN9A Q15858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31301486 0.87 SCN10A (0.52) SCN10ASCN2AHDAC8ALOX5SCN9A
SCHEMBL31301360 0.86 GPBAR1 (0.53) SCN10ASCN2AGPBAR1LTC4SSCN9A
SCHEMBL31301539 0.84 SCN10A (0.44) SCN10ASCN2AGPBAR1KDM1ACYP19A1
SCHEMBL31301522 0.83 GPBAR1 (0.46) SCN10ASCN2AGPBAR1CYP19A1LTC4S
SCHEMBL31301499 0.83 NPSR1 (0.45) SCN10ASCN2AGPBAR1CYP19A1GCGR
SCHEMBL31301406 0.79 KMO (0.49) GPBAR1HDAC8KDM1AKLRK1MICA
SCHEMBL31301363 0.76 GPBAR1 (0.42) SCN10AGPBAR1SCN9A
SCHEMBL31301435 0.75 SCN10A (0.53) SCN10ASCN2AGPBAR1
SCHEMBL31301619 0.75 MLYCD (0.46) SCN10ASCN2AGPBAR1KLRK1MICA
SCHEMBL31301529 0.75 SCN10A (0.63) SCN10ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727549-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIV GEORGIA (US) 2026-04-09 US disclosed
WO-2024258900-A2 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097046-A1 PLASMODIUM FALCIPARUM BLOOD STAGE INHIBITORS SUB1, PFN1, HCCS SCN10A 3171/4885SCN2A 2686/4885GPBAR1 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.