Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GPR18 | Q14330 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Paxilline SCHEMBL20857134 | 0.88 | MAPT (0.78) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13883377 | 0.87 | PGR (0.48) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13883004 | 0.87 | PGR (0.48) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13882665 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13882804 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13882809 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13882950 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13882787 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL13883003 | 0.85 | PGR (0.46) | PTPN1MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL31478906 | 0.84 | PTPN1 (0.43) | PTPN1MAPTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567547-B | Preparation method and application of indole diterpenoid compounds and derivatives thereof derived from endophytic fungi of schisandra chinensis | 中国科学院昆明植物研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-117567547-A | Preparation method and application of indole diterpenoid compounds and derivatives thereof derived from endophytic fungi of schisandra chinensis | 中国科学院昆明植物研究所 | 2024-02-20 | — | — | CN | claimed |
| US-20230145729-A1 | INDOLE DITERPENE BIOSYNTHESIS | GRASSLANZ TECHNOLOGY LIMITED (NZ) | 2023-05-11 | — | — | US | claimed |
| EP-4125340-A1 | INDOLE DITERPENE BIOSYNTHESIS | Grasslanz Technology Limited (NZ) | 2023-02-08 | — | — | EP | claimed |
| WO-2021201700-A1 | INDOLE DITERPENE BIOSYNTHESIS | GRASSLANZ TECHNOLOGY LIMITED (NZ) | 2021-10-07 | — | — | WO | claimed |
| EP-3740063-A1 | EPICHLOË ENDOPHYTE | Grasslanz Technology Limited (NZ) | 2020-11-25 | — | — | EP | claimed |
| WO-2019162816-A1 | EPICHLOË ENDOPHYTE | GRASSLANZ TECHNOLOGY LIMITED (NZ) | 2019-08-29 | — | — | WO | claimed |
| EP-3162438-A1 | POLYMER SUPPORTED VICINAL DIAMINES AND THEIR USE AS CATALYST IN THE HAJOS-PARRISH-ENDER-SAUSER-WIECHERT AND ROBINSON ANNULATION REACTIONS | Fundació Institut Català d'Investigació Química (ES) | 2017-05-03 | — | — | EP | claimed |
| US-20050239787-A1 | Novel maxi-k channel blockers, methods of use and process for making the same | MERCK & CO. INC. | 2005-10-27 | — | — | US | claimed |
| EP-1515730-A4 | NOVEL MAXI-K CHANNEL BLOCKERS, METHODS OF USE AND PROCESS FOR MAKING THE SAME | MERCK & CO INC (US) | 2005-07-20 | — | — | EP | claimed |
| EP-1515730-A1 | NOVEL MAXI-K CHANNEL BLOCKERS, METHODS OF USE AND PROCESS FOR MAKING THE SAME | Merck & Co., Inc. (US) | 2005-03-23 | — | — | EP | claimed |
| WO-2003105868-A1 | NOVEL MAXI-K CHANNEL BLOCKERS, METHODS OF USE AND PROCESS FOR MAKING THE SAME | MERCK & CO., INC. (US) | 2003-12-24 | — | — | WO | claimed |
| US-4973601-A | METABOLITES CONTAINING INDOLE GROUP | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1990-11-27 | — | — | US | claimed |
| CN-121204202-A | Preparation method and application of insecticidal and antifeedant indole diterpenoid compound | 中国科学院沈阳应用生态研究所 | 2025-12-26 | — | — | CN | disclosed |
| CN-121160824-A | Preparation method and application of protein tyrosine phosphatase 1B inhibitory activity indole diterpenoid compound | 中国科学院沈阳应用生态研究所 | 2025-12-19 | — | — | CN | disclosed |
| US-20250137015-A1 | YEAST PLATFORM FOR RENEWABLE INDUSTRIAL TERPENE PRODUCTION | Wang, Zhen (US) | 2025-05-01 | — | — | US | disclosed |
| US-5227396-A | Biodegradable insecticides from fungi | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1993001721-A1 | SULPININE, SECOPENITREM B AND AFLATREM B ANTIINSECTAN METABOLITES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1993-02-04 | — | — | WO | disclosed |
| US-5130326-A | Plant extracts as insecticides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1992-07-14 | — | — | US | disclosed |
| US-4973601-A | METABOLITES CONTAINING INDOLE GROUP | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1990-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239787-A1 | Novel maxi-k channel blockers, methods of use and process for making the same | KCNJ11, KCNJ1, KCNJ2 | PTPN1 4716/4885MAPT 1450/4885MEN1 189/4885 |
| US-20230145729-A1 | INDOLE DITERPENE BIOSYNTHESIS | INMT, PNMT, COASY | PTPN1 3891/4885MAPT 3924/4885MEN1 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.