SCHEMBL3137844

SCHEMBL3137844

O=C(O)c1ccc(C(=O)O)c(C#Cc2cccc3ccccc23)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
PTPN1 P18031 1/20 0.50
NR4A1 P22736 1/20 0.49
NR4A2 P43354 1/20 0.49
NR4A3 Q92570 1/20 0.49
SLC16A3 O15427 2/20 0.46
WDR5 P61964 1/20 0.46
LDHA P00338 1/20 0.45
KDM4E B2RXH2 2/20 0.44
CDC25B P30305 1/20 0.44
PLA2G2D Q9UNK4 1/20 0.43
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MCL1 Q07820 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN2A Q12879 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5667342 0.85 SLC16A3 (0.46) HSD17B10PTPN1NR4A1NR4A2NR4A3
SCHEMBL3130959 0.84 NR4A1 (0.63) HSD17B10PTPN1NR4A1NR4A2NR4A3
SCHEMBL1713039 0.80 HNF4A (0.51) HSD17B10PTPN1SLC16A3KDM4ECDC25B
SCHEMBL3130205 0.78 NR4A1 (0.59) HSD17B10PTPN1NR4A1NR4A2NR4A3
SCHEMBL5669452 0.78 KDM4E (0.45) HSD17B10PTPN1KDM4ECDC25BKMT2A
SCHEMBL28738493 0.77 NR4A1 (0.58) HSD17B10NR4A1NR4A2NR4A3WDR5
SCHEMBL5667285 0.75 KMO (0.50) SLC16A3KDM4ECDC25BMCL1ACMSD
Naphthoic Acid SCHEMBL11300621 0.75 NR4A1 (0.70) HSD17B10PTPN1NR4A1NR4A2NR4A3
Naphthalene SCHEMBL28213981 0.75 KDM4E (0.49) HSD17B10PTPN1NR4A1NR4A2NR4A3
SCHEMBL27503365 0.75 HNF4A (0.46) SLC16A3KDM4ECDC25BNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2344568-B1 ACETYLENIC POLYAMIDE NEXAM CHEMICAL AB (SE) 2017-12-20 EP claimed
CN-115197565-B Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, process for its production and use thereof 阿科玛法国公司 2024-10-11 CN disclosed
CN-115197565-A Semi-crystalline polyamide composition based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-10-18 CN disclosed
CN-110446740-B Semi-crystalline polyamide compositions based on short diamines with high glass transition temperature, method for the production thereof and use thereof 阿科玛法国公司 2022-07-12 CN disclosed
CN-110431169-B Semi-crystalline polyamide composition having a high glass transition temperature and a high melting temperature, method for preparing same and use thereof 阿科玛法国公司 2022-05-17 CN disclosed
CN-107949596-B Semi-crystalline polyamide component with high glass transition temperature for composite materials, method for the production thereof and use thereof 阿科玛法国公司 2021-02-02 CN disclosed
CN-108026267-B Semi-crystalline polyamide composition with high glass transition temperature for thermoplastic materials, method for the production thereof and use thereof 阿科玛法国公司 2021-02-02 CN disclosed
WO-2010036175-A1 MOULDED ARTICLE OBTAINED FROM ACETYLENIC POLYAMIDE NEXAM CHEMICALS (SE) 2010-04-01 WO disclosed