Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.47 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17624335 | 0.96 | CYP2D6 (0.47) | CYP2D6ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL2862442 | 0.88 | ALDH1A1 (0.60) | ALDH1A1MAPK1KMT2ALMNATP53 | |
| SCHEMBL30958119 | 0.87 | MEN1 (0.47) | OPRD1OPRK1KMT2ACHRM2CHRM4 | |
| SCHEMBL23249973 | 0.87 | MEN1 (0.47) | OPRD1OPRK1KMT2ACHRM2CHRM4 | |
| SCHEMBL12526355 | 0.84 | CYP2D6 (0.69) | CYP2D6ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL1207130 | 0.84 | OPRD1 (0.53) | CYP2D6ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL8210703 | 0.83 | KMT2A (0.55) | ALDH1A1KMT2ALMNATP53THRB | |
| SCHEMBL2381460 | 0.81 | CYP2D6 (0.59) | CYP2D6ALDH1A1USP2CYP3A4MAPK1 | |
| SCHEMBL5569584 | 0.81 | GPR119 (0.58) | ALDH1A1KMT2ALMNATP53THRB | |
| SCHEMBL11932534 | 0.81 | FAAH (0.57) | ALDH1A1KMT2ALMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229393-A1 | HPK1 DEGRADERS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-11-07 | — | — | WO | disclosed |