Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151879 | 1.00 | TSHR (0.50) | TSHRAGBL2AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL30911087 | 0.85 | MEN1 (0.52) | TSHRAGBL2AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL1699587 | 0.85 | MEN1 (0.52) | TSHRAGBL2AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL16009828 | 0.85 | P2RX7 (0.43) | TSHRAGBL2CYP2C9ALDH1A1KDM4E | |
| SCHEMBL29852214 | 0.83 | ICMT (0.43) | CYP2C9ALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL19290104 | 0.83 | P2RX7 (0.45) | AGBL2CYP2C9ALDH1A1KDM4EMEN1 | |
| SCHEMBL5427170 | 0.81 | FFAR1 (0.49) | CYP2C9ALDH1A1KDM4EMEN1CYP1A2 | |
| SCHEMBL24685984 | 0.80 | P2RX7 (0.49) | ALDH1A1KDM4EP2RX7ANO1 | |
| SCHEMBL29471363 | 0.80 | TSHR (0.53) | TSHRAGBL2AKR1C3AKR1C2CXCL8 | |
| SCHEMBL2578143 | 0.80 | CXCL8 (0.57) | TSHRCYP2C9ALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490451-A | Compounds as positive modulators of calcium activated chloride channels | TMEM16A有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-111683926-B | Compounds of formula (I) | 企业治疗学有限公司 | 2024-11-08 | — | — | CN | disclosed |