Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8640344 | 0.84 | ALOX5 (0.40) | CA12CA1CA2CA9CA14 | |
| Hydrochloric Acid SCHEMBL454032 | 0.80 | CA12 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL31307331 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9CA14 | |
| SCHEMBL458456 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9CA14 | |
| Hydrochloric Acid SCHEMBL31307330 | 0.77 | HDAC8 (0.38) | TRPA1ALDH1A1ALOX15HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL31307329 | 0.77 | HDAC8 (0.38) | TRPA1ALDH1A1ALOX15HSD17B10LMNA | |
| Bromide SCHEMBL454874 | 0.76 | CA12 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL457069 | 0.74 | PTGS1 (0.40) | CA12CA1CA2CA9CA7 | |
| Hydrochloric Acid SCHEMBL31307327 | 0.74 | GUSB (0.45) | TRPA1ALDH1A1ALOX15HSD17B10TP53 | |
| Acetic Acid SCHEMBL457559 | 0.72 | CA12 (0.39) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024223200-A1 | SWITCHABLE ADSORPTION MATERIALS BASED ON PUNICINES AND YLIDES FOR SELECTIVE SEPARATION AND RECYCLING OF METAL CATIONS AND METAL-CONTAINING ANIONS FROM COMPLEX SOLUTIONS | Technische Universität Clausthal (DE) | 2024-10-31 | — | — | WO | disclosed |
| EP-4454748-A1 | SWITCHABLE ADSORPTION MATERIALS BASED ON PUNICINES AND YLIDES FOR SELECTIVE SEPARATION AND RECYCLING OF METAL CATIONS AND METAL-CONTAINING ANIONS FROM COMPLEX SOLUTIONS | Technische Universität Clausthal (DE) | 2024-10-30 | — | — | EP | disclosed |