Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31307329 | 1.00 | HDAC8 (0.38) | HDAC8TRPA1ALDH1A1LCKNQO2 | |
| Hydrochloric Acid SCHEMBL31307327 | 0.80 | GUSB (0.45) | TRPA1ALDH1A1LCKNQO2MEN1 | |
| Hydrochloric Acid SCHEMBL8640344 | 0.80 | ALOX5 (0.40) | ALDH1A1LMNAALOX15HSD17B10TTR | |
| Hydrochloric Acid SCHEMBL31307333 | 0.77 | ACHE (0.39) | TRPA1ALDH1A1LMNATP53ALOX15 | |
| Hydrochloric Acid SCHEMBL454032 | 0.76 | CA12 (0.38) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL31307331 | 0.74 | CA12 (0.39) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL458456 | 0.74 | CA12 (0.39) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Bromide SCHEMBL454874 | 0.72 | CA12 (0.38) | ALDH1A1MEN1KMT2APOLBMAPT | |
| Sulfuric Acid SCHEMBL457707 | 0.68 | PTGS1 (0.43) | ALDH1A1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL10970999 | 0.66 | PELI1 (0.54) | TRPA1ALDH1A1LCKNQO2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024223200-A1 | SWITCHABLE ADSORPTION MATERIALS BASED ON PUNICINES AND YLIDES FOR SELECTIVE SEPARATION AND RECYCLING OF METAL CATIONS AND METAL-CONTAINING ANIONS FROM COMPLEX SOLUTIONS | Technische Universität Clausthal (DE) | 2024-10-31 | — | — | WO | disclosed |
| EP-4454748-A1 | SWITCHABLE ADSORPTION MATERIALS BASED ON PUNICINES AND YLIDES FOR SELECTIVE SEPARATION AND RECYCLING OF METAL CATIONS AND METAL-CONTAINING ANIONS FROM COMPLEX SOLUTIONS | Technische Universität Clausthal (DE) | 2024-10-30 | — | — | EP | disclosed |