Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200624 | 0.90 | KDM4E (0.51) | LMNASMN1; SMN2MAPTKDM4EAPP | |
| SCHEMBL22425685 | 0.87 | ALDH1A1 (0.48) | LMNASMN1; SMN2L3MBTL1MAPTKDM4E | |
| SCHEMBL24080293 | 0.87 | ALDH1A1 (0.48) | LMNASMN1; SMN2L3MBTL1MAPTKDM4E | |
| SCHEMBL18569789 | 0.84 | KDM4E (0.47) | LMNASMN1; SMN2MAPTKDM4EAPP | |
| SCHEMBL13904260 | 0.81 | L3MBTL1 (0.56) | LMNASMN1; SMN2L3MBTL1MAPTKDM4E | |
| SCHEMBL584489 | 0.81 | TACR2 (0.62) | LMNASMN1; SMN2L3MBTL1MAPTKDM4E | |
| SCHEMBL29446267 | 0.81 | TACR2 (0.62) | LMNASMN1; SMN2L3MBTL1MAPTKDM4E | |
| SCHEMBL21738205 | 0.80 | TACR2 (0.53) | LMNASMN1; SMN2KDM4EAPPALDH1A1 | |
| SCHEMBL28535059 | 0.80 | POLB (0.53) | LMNASMN1; SMN2MAPTKDM4EAPP | |
| SCHEMBL5213944 | 0.79 | TACR2 (0.54) | LMNASMN1; SMN2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12173018-B2 | Penicillin-binding protein inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2024-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12173018-B2 | Penicillin-binding protein inhibitors | PEPD, BPGM, EBPL | LMNA 3468/4885SMN1; SMN2 3101/4885L3MBTL1 455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.