Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31308012 | 0.88 | LOXL2 (0.39) | LOXL2ABHD6IDH1 | |
| SCHEMBL29277464 | 0.82 | LOXL2 (0.31) | LOXL2MET | |
| SCHEMBL31308005 | 0.82 | HCRTR1 (0.37) | — | |
| SCHEMBL31307995 | 0.80 | HCRTR2 (0.35) | LOXL2 | |
| SCHEMBL31307975 | 0.75 | MALT1 (0.43) | IDH1 | |
| SCHEMBL30503552 | 0.74 | TIPARP (0.31) | — | |
| SCHEMBL30503553 | 0.74 | HCRTR1 (0.35) | — | |
| SCHEMBL30503585 | 0.74 | TTR (0.34) | — | |
| SCHEMBL30503582 | 0.74 | MBOAT4 (0.36) | — | |
| SCHEMBL30503604 | 0.74 | FFAR4 (0.36) | LOXL2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |