Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31307990 | 0.88 | LOXL2 (0.34) | LOXL2ABHD6IDH1 | |
| SCHEMBL29277464 | 0.84 | LOXL2 (0.31) | LOXL2 | |
| SCHEMBL25301218 | 0.83 | LOXL2 (0.47) | LOXL2ABHD6IDH1 | |
| SCHEMBL25301249 | 0.79 | LOXL2 (0.35) | LOXL2IDH1 | |
| SCHEMBL25297104 | 0.78 | LOXL2 (0.46) | LOXL2ABHD6 | |
| SCHEMBL29497063 | 0.78 | LOXL2 (0.46) | LOXL2ABHD6 | |
| SCHEMBL31307974 | 0.75 | LIPE (0.44) | ABHD6 | |
| SCHEMBL25324473 | 0.74 | LOXL2 (0.40) | LOXL2ABHD6 | |
| SCHEMBL30553220 | 0.74 | LOXL2 (0.40) | LOXL2ABHD6 | |
| SCHEMBL30503523 | 0.73 | LOXL2 (0.34) | LOXL2ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |