Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253196 | 0.83 | LOXL2 (0.38) | HCRTR2HCRTR1LOXL2 | |
| SCHEMBL29277452 | 0.82 | HCRTR2 (0.40) | HCRTR2HCRTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31308005 | 0.81 | HCRTR1 (0.37) | HCRTR2HCRTR1 | |
| SCHEMBL25145643 | 0.80 | HCRTR2 (0.33) | HCRTR2HCRTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30396039 | 0.80 | HCRTR2 (0.33) | HCRTR2HCRTR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31307990 | 0.80 | LOXL2 (0.34) | LOXL2 | |
| SCHEMBL30395753 | 0.79 | GPR119 (0.48) | LOXL2 | |
| SCHEMBL25298984 | 0.79 | GPR119 (0.48) | LOXL2 | |
| SCHEMBL30503585 | 0.78 | TTR (0.34) | HCRTR2HCRTR1 | |
| SCHEMBL30503582 | 0.78 | MBOAT4 (0.36) | PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |